E-ISSN 2146-3077
Original Article
In vitro Assessment of Anti - Cutaneous Leishmaniasis Activity of Some Sudanese Plants
1 Institute of Nuclear Medicine, Molecular Biology and Oncology, University of Gezira, Sudan  
2 Department of Pathology, Faculty of Technology, Omdurman, Sudan  
3 Faculty of Dermatology, Faculty of Medicine, University of Gezera, Sudan  
4 Ministry of Education and Scientific Research, Khartoum, Sudan  
5 Department of Medicine, Faculty of Medicine, Khartoum, Sudan  
Turkiye Parazitol Derg 2005; 29: 3-6

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Key Words: Leishmaniasis, cutaneous, herbal therapy, in vitro
Abstract

Examination of crude methanol extracts of four Sudanese plants (Azadirachta indica, Acacia nilotica, Balanites aegyptiaca and Allium sativa) revealed that only three species had a considerable in-vitro anti-leishmanial activity on Leishmania major promastigotes. The plants Azadrachta indica, Allium sativa, and Acacia nilotica gave a LC50 of 10.2, 4.94, and 89.38 µg/ml, respectively. Extracts of Balanites aegyptiaca had a moderate biological activity on L major promastigotes. 

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