E-ISSN 2146-3077
Original Article
Culture of Plasmodium berghei ANKA in BALB/c Mice and Research on Experimental Cerebral Malaria
1 Harran Üniversitesi Tıp Fakültesi Tıbbi Biyoloji Anabilim Dalı  
2 Harran Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı  
3 Harran Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı, Şanlıurfa  
Turkiye Parazitol Derg 2005; 29: 154-156

Key Words: Plasmodium berghei, cerebral malaria, BALB/c mice

Plasmodium berghei ANKA 6653 isolates that cause malaria in rodents were cultured in BALB/c mice in this study. Each of the BALB/c mice were injected intraperitoneally with 0.3 ml from a stock solution containing 160.000 parasites/ml. Percentage values of parasitemia at day 3, 6, 9 and 15 after injection were recorded and graphed. The neurological signs after day 3 were recorded in this study. At the end of day 15, cerebral tissues of dead mice were taken and the accumulation of hemorrhages was investigated. A total of 97 inbred BALB/c mice weighing approximately 17-20 gr. were used in this study. 

Key Words
Reviewer's Corner
AVES | Copyright © 2018 Turkish Parasitology Association | Latest Update: 10.10.2018